Promega Corporation

ASK1 Kinase Enzyme System

See All Kinase Enzyme Systems
Recombinant human ASK1 (649–946) was expressed by baculovirus in Sf9 cells using an N-terminal GST tag. ASK1, also known as MAPKKK5, activates MKK3, MKK4 (SEK1) and MKK6. Overexpression of ASK1 induces apoptotic cell death, and ASK1 is activated in cells treated with tumor necrosis factor-alpha. ASK1 interacts with members of the TRAF family and is activated by TRAF2 in the TNF-signaling pathway. After activation by TRAF2, ASK1 activates MKK4, which in turn activates JNK. Thus, ASK1 is a mediator of TRAF2-induced JNK activation.

ADP-Glo™ Kinase Assay is a luminescent kinase ass...

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ASK1 Kinase Enzyme System

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ASK1 Kinase Enzyme System

 Components

10μg
- V3881 ¥ 5,795.00 Add to cart

ASK1 Kinase Enzyme System

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ASK1 Kinase Enzyme System

 Components

1mg
- V3882 ¥ 71,143.00 Add to cart

ADP-Glo™ Kinase Assay + ASK1 Kinase Enzyme System

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ADP-Glo™ Kinase Assay + ASK1 Kinase Enzyme System

 Components

  • ASK1 Kinase Enzyme System

    V38811 x 10μg
  • ADP-Glo™ Kinase Assay

    V91011 x 1,000 assays
1 each
- V9481 ¥ 8,713.00 Add to cart


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Storage Conditions

Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.

For product intended use please see Patents & Disclaimers tab.

Use Restrictions

V3881, V3882, V9481 For Research Use Only. Not for Use in Diagnostic Procedures.

Patents - Disclaimers

V9481 U.S. Pat. Nos. 7,083,911, 7,452,663 and 7,732,128 and other patents.

V9481 U.S. Pat. No. 7,700,310 and other patents and patents pending.

V9481 U.S. Pat. No. 7,741,067 and other patents and patents pending.

V9481 U.S. Pat. Nos. 6,602,677, 7,241,584 and 8,030,017 and other patents and patents pending.

V9481 U.S. Pat. No. 8,183,007 and other patents pending.

V9481 Licensed from Lonza Nottingham Ltd. under U.S. Pat. Nos. 6,599,711 and 6,911,319 and other pending and issued patents.

V9481 The method of recombinant expression of Coleoptera luciferase is covered by U.S. Pat. Nos. 5,583,024, 5,674,713 and 5,700,673.

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